Deflux Meltab 10pcs - ePharma
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Deflux Meltab 10pcs

Type: Tablet

Pack Size: 10 Pcs

Generic Name: Domperidone Maleate 10mg 

Company Name: Beximco Pharmaceuticals Ltd.


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Discount Price: ৳ 32.9
MRP: ৳ 35 6% Off

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✅ Description:

Indications

A prescription drug called Deflux Meltab Dispersible is used to treat nausea, vomiting, and indigestion. It enhances food movement in the stomach, which helps with digestion, and blocks the brain chemical that causes nausea or vomiting. Before meals, take Deflux Meltab Dispersible in the dosage and for the recommended amount of time.

Pharmacology

Domperidone is a dopamine antagonist that mainly blocks dopamine receptors located in the chemoreceptor activation zone (CTZ) and stomach. Its gastrointestinal motility is based on its blocking effect on dopamine receptors that affect gastrointestinal motility. Due to its weak permeability to the blood-brain barrier, domperidone has almost no effect on dopamine receptors in the brain, thus eliminating mental and neurological side effects. Domperidone restores the normal movement and tension of the upper gastrointestinal tract, promotes gastric emptying, improves gastric antrum and duodenal peristalsis, and regulates pyloric contraction. Domperidone also increases esophageal motility and reduces esophageal sphincter pressure, thereby preventing the reflux of stomach contents.

Dosage & Administration

If necessary, take Deflux before bedtime and between 15 and 30 minutes before meals. The usual dosages for oral administration of those who use domperidone include:

  • Adults: 1020 mg (12 tablets or 1020 ml suspension), once every 68 hours a day. The maximum dose of domperidone is 80 mg per day.
  • Children: 24 ml suspension/10 kg body weight or 0.40.8 ml pediatric drops/10 kg body weight every 68 hours every day.

In acute and subacute situations (mainly acute nausea and vomiting): 

  • Adults: 20 mg (2 tablets or 20 ml suspension), every 68 hours per day
  • Children: 0.20.4 mg/kg (24 ml suspension) /10 kg or 0.40.8 ml pediatric drops/10 kg) body weight, once every 68 hours a day. (In acute nausea and vomiting, the maximum treatment period is 12 weeks).

Indigestion symptoms: 

  • Adults: 1020 mg (12 tablets or 1020 ml suspension), once every 68 hours a day.
  • Children: 0.20.4 mg/kg (24 ml suspension/10 kg or 0.40.8 ml pediatric drops/10 kg) weight every 68 hours per day.

Rectal suppositories: 

  • Adults (including the elderly): 3060 mg every 48 hours.
  • Children: The maximum daily rectal dose for children weighing 10 to 25 kg is 30 mg. If necessary, it can be taken in divided doses throughout the day.
  • The maximum treatment period is 12 weeks.

Interaction

Deflux can reduce the risk of bromocriptine-causing hypoprolactin. The effect of domperidone on GI function can be antagonized by antimuscarinic drugs and opioid analgesics. Caution should be exercised when domperidone is administered in combination with MAO (monoamine oxidase) inhibitors.

Contraindications

Deflux is contraindicated in patients and newborns who are known to be allergic to this drug. Domperidone should not be used when gastrointestinal irritation could be dangerous, ie gastrointestinal bleeding, mechanical obstruction, or perforation. Prolactin-releasing pituitary tumors (prolactinomas) are also contraindicated.

Side Effects

Domperidone can cause hyperprolactinemia (1.3%). This can cause galactorrhea, breast enlargement, pain, and decreased libido. Dry mouth (1%), thirst, headache (1.2%), nervousness, drowsiness (0.4%), diarrhea (0.2%), rash, and itching ( 0.1%). In clinical studies, 0.05% of patients had extrapyramidal reactions.

Pregnancy & Lactation

The safety of domperidone has not been proven, so its use during pregnancy is not recommended. Animal studies have not shown teratogenic effects on the fetus. Domperidone can cause galactorrhea and improve postpartum lactation. It is secreted in breast milk, but the amount is very small and not enough to be considered harmful.

Precautions & Warnings

The safety of Deflux has not been proven, so its use during pregnancy is not recommended. Animal studies have not shown teratogenic effects on the fetus. Domperidone can cause galactorrhea and improve postpartum lactation. It is secreted in breast milk, but the amount is very small and not enough to be considered harmful.

Storage Conditions

Store below 30 ° C protected from light and moisture. Keep out of the reach of children.

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Check our pricing section for Deflux Meltab 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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